This report presents general guidelines for preparing a case study of public-private partnership in the health sector. Based on the guidelines, a case study is undertaken in partnership between a private medical college and a public hospital in the city of Abbottabad in NWFP. This case study highlights how a successful partnership can be evolved in the presence of ‘synergy’ between partners, strong leadership, shared objectives, success in coalition building, appropriate changes in governance structure, proper legal framework, building of safeguards and outside patronage.